Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | FRK | P42685 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.43 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5574792 | 0.78 | NSD3 (0.55) | NSD3PTGS2TSHRLMNAPRKD3 | |
| SCHEMBL1009513 | 0.75 | NSD3 (0.83) | NSD3PTGS2TSHRLMNAPRKD3 | |
| SCHEMBL5720398 | 0.73 | FAAH (0.56) | NSD3PTGS2TSHRLMNAFAAH | |
| SCHEMBL29874438 | 0.73 | NSD3 (0.80) | NSD3PTGS2TSHRLMNAPRKD3 | |
| SCHEMBL11335769 | 0.72 | PTGS2 (0.51) | NSD3PTGS2TSHRLMNAPRKD3 | |
| SCHEMBL11096496 | 0.72 | NSD3 (0.53) | NSD3PTGS2TSHRLMNAPRKD3 | |
| SCHEMBL4805174 | 0.71 | PTGS2 (0.63) | NSD3PTGS2TSHRLMNAPRKD3 | |
| SCHEMBL5748234 | 0.71 | MAPK14 (0.60) | NSD3PTGS2TSHRLMNACSNK1D | |
| SCHEMBL20466312 | 0.71 | MAPK14 (0.60) | NSD3PTGS2TSHRLMNAPRKD3 | |
| SCHEMBL15458774 | 0.71 | MAPK13 (0.60) | NSD3PTGS2TSHRLMNAPRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442448-A2 | Heterocyclic carboxylic acids and esters | Bristol-Myers Squibb Company (US) | 1991-08-21 | — | — | EP | disclosed |