Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.54 |
| ▸ | PRKACA | P17612 | 1/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | IKBKB | O14920 | 2/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | IL2 | P60568 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9843028 | 0.89 | CNR1 (0.51) | CNR1PRKACAROCK1HDAC6NPC1 | |
| SCHEMBL9843027 | 0.86 | CNR1 (0.52) | CNR1HDAC6NPC1RAB9AHSD17B2 | |
| SCHEMBL9842919 | 0.81 | CYP1A2 (0.42) | CNR1NPC1RAB9AHSD17B2PTPN1 | |
| SCHEMBL9842925 | 0.80 | CNR1 (0.39) | CNR1NPC1RAB9AIL2MAPT | |
| SCHEMBL9842940 | 0.78 | CNR1 (0.53) | CNR1IKBKBIL2MAPK1CYP1A2 | |
| SCHEMBL9842993 | 0.78 | IL2 (0.48) | HDAC6NPC1RAB9AIL2MAPK1 | |
| SCHEMBL9842883 | 0.78 | CNR1 (0.52) | CNR1IL2MAPK1CYP1A2APOBEC3A | |
| SCHEMBL9842960 | 0.77 | KDR (0.42) | CNR1NPC1RAB9AIL2MAPT | |
| SCHEMBL9842938 | 0.76 | IL2 (0.39) | CNR1NPC1RAB9APTPN1IL2 | |
| SCHEMBL9842957 | 0.75 | CNR1 (0.45) | CNR1NPC1RAB9AIL2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440503-A1 | 4-Isoxazolecarboxamide derivatives | SYNTEX (U.S.A.) INC. (US) | 1991-08-07 | — | — | EP | disclosed |