Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 2/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | STAT3 | P40763 | 2/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842822 | 0.88 | NPC1 (0.43) | IL2DEGS1NPC1RAB9ACYP1A2 | |
| SCHEMBL9842892 | 0.85 | HDAC6 (0.44) | IL2HDAC6TRPV1 | |
| SCHEMBL9842919 | 0.84 | CYP1A2 (0.42) | IL2NPC1RAB9APTPN11CYP1A2 | |
| SCHEMBL9842940 | 0.84 | CNR1 (0.53) | IL2CYP1A2MAPK1APOBEC3AAPOBEC3G | |
| SCHEMBL9842938 | 0.84 | IL2 (0.39) | IL2NPC1RAB9APTPN2PTPN11 | |
| SCHEMBL9843028 | 0.81 | CNR1 (0.51) | DEGS1HDAC6NPC1RAB9A | |
| SCHEMBL9842960 | 0.81 | KDR (0.42) | IL2NPC1RAB9ACYP1A2MAPK1 | |
| SCHEMBL9843027 | 0.81 | CNR1 (0.52) | IL2HDAC4HDAC6NPC1RAB9A | |
| SCHEMBL9842925 | 0.79 | CNR1 (0.39) | IL2NPC1RAB9ACYP1A2MAPK1 | |
| SCHEMBL9843014 | 0.79 | NPC1 (0.60) | STAT3HDAC6NPC1PTGS1KCNQ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440503-A1 | 4-Isoxazolecarboxamide derivatives | SYNTEX (U.S.A.) INC. (US) | 1991-08-07 | — | — | EP | disclosed |