Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842991 | 0.89 | CNR1 (0.54) | CNR1SMN1; SMN2KDM4ENPC1MAPT | |
| SCHEMBL9842919 | 0.87 | CYP1A2 (0.42) | CNR1SMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL9842960 | 0.85 | KDR (0.42) | CNR1SMN1; SMN2KDM4ELMNACSNK2A2 | |
| SCHEMBL9842940 | 0.84 | CNR1 (0.53) | CNR1 | |
| SCHEMBL9842938 | 0.81 | IL2 (0.39) | CNR1SMN1; SMN2CSNK2A2CSNK2A1NPC1 | |
| SCHEMBL9842993 | 0.81 | IL2 (0.48) | NPC1HDAC6DEGS1RAB9A | |
| SCHEMBL9842925 | 0.81 | CNR1 (0.39) | CNR1SMN1; SMN2NPC1MAPTGAA | |
| SCHEMBL9843027 | 0.81 | CNR1 (0.52) | CNR1SMN1; SMN2KDM4ELMNANPC1 | |
| SCHEMBL9843089 | 0.79 | RAB9A (0.64) | SMN1; SMN2KDM4ELMNANPC1MAPT | |
| SCHEMBL9842957 | 0.76 | CNR1 (0.45) | CNR1SMN1; SMN2NPC1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440503-A1 | 4-Isoxazolecarboxamide derivatives | SYNTEX (U.S.A.) INC. (US) | 1991-08-07 | — | — | EP | disclosed |