Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728246 | 0.85 | CHRNB2 (0.40) | CHRNB2CHRNA4MEN1KMT2AALDH1A1 | |
| SCHEMBL9504024 | 0.78 | CHRNB2 (0.42) | CHRNB2CHRNA4MEN1KMT2AALDH1A1 | |
| SCHEMBL7637289 | 0.76 | CHRNB2 (0.39) | CHRNB2CHRNA4MEN1KMT2AALDH1A1 | |
| SCHEMBL7637297 | 0.76 | CHRNB2 (0.39) | CHRNB2CHRNA4MEN1KMT2AALDH1A1 | |
| SCHEMBL8926511 | 0.74 | ALDH1A1 (0.43) | CHRNB2CHRNA4MEN1KMT2AALDH1A1 | |
| SCHEMBL2755020 | 0.74 | ALDH1A1 (0.43) | CHRNB2CHRNA4MEN1KMT2AALDH1A1 | |
| SCHEMBL8191142 | 0.73 | ALDH1A1 (0.40) | CHRNB2CHRNA4MEN1KMT2AALDH1A1 | |
| SCHEMBL13240181 | 0.73 | ALDH1A1 (0.38) | CHRNB2CHRNA4MEN1KMT2AALDH1A1 | |
| SCHEMBL9729443 | 0.73 | ALDH1A1 (0.39) | CHRNB2CHRNA4MEN1KMT2AALDH1A1 | |
| SCHEMBL7036880 | 0.73 | CHRNB2 (0.42) | CHRNB2CHRNA4MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418199-A2 | Guanidine derivatives | CIBA-GEIGY AG (CH) | 1991-03-20 | — | — | EP | disclosed |