Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9843035 | 0.85 | CHRNB2 (0.37) | CHRNB2CHRNA4ALDH1A1GAAF10 | |
| SCHEMBL8191142 | 0.85 | ALDH1A1 (0.40) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9504024 | 0.82 | CHRNB2 (0.42) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7637297 | 0.81 | CHRNB2 (0.39) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL7637289 | 0.81 | CHRNB2 (0.39) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9729443 | 0.80 | ALDH1A1 (0.39) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9843140 | 0.79 | RIPK1 (0.47) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL2755020 | 0.79 | ALDH1A1 (0.43) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8926511 | 0.79 | ALDH1A1 (0.43) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL13240181 | 0.78 | ALDH1A1 (0.38) | CHRNB2CHRNA4ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166164-A | Nontoxic to mammals, fish, and crustaceans; nonphytotoxic | AGRO-KANESHO CO., LTD. (JP) | 1992-11-24 | — | — | US | claimed |
| CN-1050186-A | Guanidine derivative | CIBA GEIGY AG (CH) | 1991-03-27 | — | — | CN | claimed |
| EP-0418199-A2 | Guanidine derivatives | CIBA-GEIGY AG (CH) | 1991-03-20 | — | — | EP | claimed |
| CN-1050186-A | Guanidine derivative | CIBA GEIGY AG (CH) | 1991-03-27 | — | — | CN | disclosed |
| EP-0418199-A2 | Guanidine derivatives | CIBA-GEIGY AG (CH) | 1991-03-20 | — | — | EP | disclosed |