Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27887659 | 0.77 | GRIN2B (0.56) | POLB | |
| Hydrochloric Acid SCHEMBL11297441 | 0.77 | LMNA (0.45) | L3MBTL1SMN1; SMN2ADRA2AADRA2BADRA2C | |
| SCHEMBL9843115 | 0.75 | POLB (0.42) | POLBSMN1; SMN2NPC1 | |
| SCHEMBL3910519 | 0.74 | HRH4 (0.62) | L3MBTL1SMN1; SMN2ADRA2AADRA2BADRA2C | |
| SCHEMBL25439793 | 0.74 | ADRA2A (0.39) | KMT2AL3MBTL1SMN1; SMN2ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL538727 | 0.73 | GRIN2D (0.63) | L3MBTL1SMN1; SMN2ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL7677579 | 0.70 | LMNA (0.47) | L3MBTL1SMN1; SMN2ADRA2AADRA2BADRA2C | |
| SCHEMBL11363646 | 0.69 | MEN1 (0.36) | KMT2AMEN1 | |
| SCHEMBL1259299 | 0.68 | SMN1; SMN2 (0.49) | POLBSMN1; SMN2CYP1A2NPC1RAB9A | |
| SCHEMBL11377489 | 0.68 | MEN1 (0.39) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418199-A2 | Guanidine derivatives | CIBA-GEIGY AG (CH) | 1991-03-20 | — | — | EP | claimed |
| CN-1050186-A | Guanidine derivative | CIBA GEIGY AG (CH) | 1991-03-27 | — | — | CN | disclosed |
| EP-0418199-A2 | Guanidine derivatives | CIBA-GEIGY AG (CH) | 1991-03-20 | — | — | EP | disclosed |