Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | OXTR | P30559 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7795446 | 0.81 | CHRNB2 (0.44) | CHRNB2CHRNA4NAMPTCYP2C9FAAH | |
| SCHEMBL9727921 | 0.81 | CHRNB2 (0.42) | CHRNB2CHRNA4NAMPTCYP2C9FAAH | |
| SCHEMBL7664015 | 0.76 | ALDH1A1 (0.43) | CHRNB2CHRNA4NAMPTCYP2C9FAAH | |
| SCHEMBL8404155 | 0.76 | ALDH1A1 (0.43) | CHRNB2CHRNA4NAMPTCYP2C9FAAH | |
| SCHEMBL9843165 | 0.75 | RECQL (0.40) | ALDH1A1KDM4EGAAL3MBTL1MAPT | |
| SCHEMBL7663609 | 0.74 | CYP2C9 (0.44) | CHRNB2CHRNA4NAMPTCYP2C9FAAH | |
| SCHEMBL7639531 | 0.74 | NAMPT (0.44) | CHRNB2CHRNA4NAMPTCYP2C9FAAH | |
| SCHEMBL9047024 | 0.73 | FPR2 (0.44) | CHRNB2CHRNA4NAMPTCYP2C9FAAH | |
| SCHEMBL9047032 | 0.73 | FPR2 (0.44) | CHRNB2CHRNA4NAMPTCYP2C9FAAH | |
| SCHEMBL7036877 | 0.73 | ALDH1A1 (0.41) | CHRNB2CHRNA4NAMPTCYP2C9FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418199-A2 | Guanidine derivatives | CIBA-GEIGY AG (CH) | 1991-03-20 | — | — | EP | claimed |
| EP-0418199-A2 | Guanidine derivatives | CIBA-GEIGY AG (CH) | 1991-03-20 | — | — | EP | disclosed |