Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192031 | 0.80 | CES2 (0.50) | CES2CES1PARP1MAOAMAOB | |
| SCHEMBL9055041 | 0.78 | PARP1 (0.48) | PARP1MAOAMAOBGRIN2BMEN1 | |
| SCHEMBL17868853 | 0.77 | CES2 (0.47) | CES2CES1PARP1MAOAMAOB | |
| SCHEMBL12942306 | 0.77 | CES2 (0.47) | CES2CES1PARP1MAOAMAOB | |
| SCHEMBL27864984 | 0.77 | CES2 (0.56) | CES2CES1PARP1HDAC1HDAC6 | |
| SCHEMBL28863383 | 0.76 | CES2 (0.60) | CES2CES1PARP1HDAC1HDAC6 | |
| SCHEMBL9845816 | 0.76 | PARP1 (0.47) | PARP1HDAC6MEN1KMT2ANPC1 | |
| SCHEMBL16959379 | 0.76 | CES2 (0.50) | CES2CES1PARP1MAOBHDAC1 | |
| SCHEMBL4368509 | 0.76 | CES2 (0.61) | CES2CES1PARP1HDAC1HDAC6 | |
| SCHEMBL30209486 | 0.76 | GPR52 (0.47) | CES2CES1PARP1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435794-A1 | Alkenyl- or heteroaryl thio, sulfone, sulfoxy herbicides | RHONE-POULENC AGROCHIMIE (FR) | 1991-07-03 | — | — | EP | disclosed |