SCHEMBL9843360

SCHEMBL9843360

Cc1ccc(-c2c(N)cccc2CNc2ccc(C=O)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.43
CYP2A6 P11509 1/20 0.40
HTT P42858 2/20 0.37
CCNE1 P24864 6/20 0.37
CDK2 P24941 6/20 0.37
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
LMNA P02545 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
FFAR1 O14842 1/20 0.35
GCGR P47871 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9843362 0.82 MAPT (0.43) MAPTCYP2A6HTTCCNE1CDK2
SCHEMBL14126210 0.74 MEN1 (0.56) MAPTCYP2A6HTTCA12CA1
SCHEMBL9843369 0.73 FFAR1 (0.36) MAPTHTTCCNE1CDK2CA12
SCHEMBL10692338 0.72 MAPT (0.46) MAPTCYP2A6HTTCA12CA1
SCHEMBL14196612 0.72 MAPT (0.61) MAPTCYP2A6HTTCA12CA1
SCHEMBL10686619 0.70 MAPT (0.44) MAPTCYP2A6HTTCA12CA1
SCHEMBL9843367 0.68 ALDH1A1 (0.56) MAPTCYP2A6HTTCA12CA1
SCHEMBL27458150 0.67 CYP3A4 (0.48) MAPTLMNATDP1SMN1; SMN2
SCHEMBL6924151 0.67 FFAR1 (0.58) CYP2A6FFAR1GCGRSMN1; SMN2
SCHEMBL10969934 0.67 AKR1B1 (0.41) LMNATDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0410285-A1 Laminated organic photosensitive material BANDO CHEMICAL INDUSTRIES, LIMITED (JP) 1991-01-30 EP disclosed