SCHEMBL9843369

SCHEMBL9843369

Cc1ccc(CNc2ccc(C=O)cc2)c(N)c1-c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 4/20 0.36
MAPT P10636 2/20 0.35
HTT P42858 1/20 0.35
FFAR4 Q5NUL3 2/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
PTGER4 P35408 2/20 0.33
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
GHSR Q92847 1/20 0.33
HDAC4 P56524 1/20 0.33
MEF2D Q14814 1/20 0.33
GAA P10253 1/20 0.33
CCNE1 P24864 1/20 0.33
CDK2 P24941 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
APP P05067 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10692338 0.76 MAPT (0.46) MAPTHTTCA12CA1CA2
SCHEMBL6924151 0.74 FFAR1 (0.58) FFAR1FFAR4HDAC3HDAC1HDAC4
SCHEMBL9843362 0.73 MAPT (0.43) FFAR1MAPTHTTFFAR4CA12
SCHEMBL9843360 0.73 MAPT (0.43) FFAR1MAPTHTTCA12CA1
SCHEMBL10686619 0.71 MAPT (0.44) MAPTHTTCA12CA1CA2
SCHEMBL511052 0.69 HTT (0.58) FFAR1HTTFFAR4CA12CA1
SCHEMBL4842309 0.68 ALDH1A1 (0.45) MAPTHTTMEN1KMT2A
SCHEMBL3962723 0.68 SMN1; SMN2 (0.47) MAPTHTTGAAMEN1KMT2A
SCHEMBL10714684 0.67 PTGS1 (0.46) HTTGAA
SCHEMBL510506 0.66 FFAR1 (0.54) FFAR1HTTFFAR4CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0410285-A1 Laminated organic photosensitive material BANDO CHEMICAL INDUSTRIES, LIMITED (JP) 1991-01-30 EP disclosed