Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.31 |
| ▸ | ADRB2 known ✓ | P07550 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL9842858 | 0.73 | LMNA (0.35) | TSHRSMN1; SMN2KDM4EHSD17B10TDP1 | |
| SCHEMBL9843329 | 0.72 | — | — | |
| Cadaverine Tartrate SCHEMBL9843345 | 0.71 | LMNA (0.56) | SMN1; SMN2KDM4EHIF1ALMNA | |
| Cadaverine Tartrate SCHEMBL5875222 | 0.62 | TSHR (0.71) | TSHRSMN1; SMN2PDE4AKDM4EHSD17B10 | |
| Cadaverine Tartrate SCHEMBL5875227 | 0.62 | TSHR (0.71) | TSHRSMN1; SMN2PDE4AKDM4EHSD17B10 | |
| Cadaverine Tartrate SCHEMBL8850451 | 0.61 | TSHR (0.59) | TSHRPDE4AKDM4ETDP1NFKB1 | |
| Cadaverine Tartrate SCHEMBL7773090 | 0.61 | TSHR (0.59) | TSHRPDE4AKDM4ETDP1NFKB1 | |
| Tartaric Acid SCHEMBL30771976 | 0.60 | TSHR (0.67) | TSHRPDE4AKDM4ETDP1NFKB1 | |
| Cadaverine Tartrate SCHEMBL282045 | 0.60 | TSHR (0.67) | TSHRPDE4AKDM4ETDP1NFKB1 | |
| Cadaverine Tartrate SCHEMBL31435552 | 0.60 | TSHR (0.91) | TSHRPDE4AKDM4EHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5004835-A | Substituted dicarboxylic acid-bis(3,5-dicarbamoyl-2,4,6-triiodoanilides), process for their production as well as X-ray contrast media containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-04-02 | — | — | US | disclosed |