SCHEMBL9843672

SCHEMBL9843672

C=CCn1cnc2cc(C(F)(F)F)ccc21.C=CCn1cnc2cc(F)ccc21

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DDR1 Q08345 3/20 0.43
TBXA2R P21731 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
QPCT Q16769 1/20 0.39
QPCTL Q9NXS2 1/20 0.39
PKM P14618 1/20 0.37
PRPS1 P60891 1/20 0.36
LMNA P02545 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
MAPT P10636 2/20 0.35
USP2 O75604 1/20 0.34
POLB P06746 1/20 0.34
GAA P10253 1/20 0.34
HTT P42858 1/20 0.34
MAPK10 P53779 1/20 0.34
PTGDR2 Q9Y5Y4 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4681375 0.93 NPSR1 (0.44) DDR1TBXA2RNPSR1QPCTQPCTL
SCHEMBL6536735 0.89 PRPS1 (0.42) TBXA2RQPCTQPCTLPRPS1LMNA
SCHEMBL10896310 0.82 PRPS1 (0.45) DDR1TBXA2RNPSR1QPCTQPCTL
SCHEMBL9771569 0.79 KDM4E (0.41) DDR1TBXA2RNPSR1QPCTQPCTL
SCHEMBL19911437 0.78 TBXA2R (0.41) DDR1TBXA2RQPCTPRPS1
SCHEMBL6758779 0.76 NPSR1 (0.51) DDR1NPSR1QPCTQPCTLPKM
SCHEMBL31202825 0.75 QPCT (0.43) DDR1TBXA2RNPSR1QPCTQPCTL
SCHEMBL21991220 0.73 PRPS1 (0.43) QPCTQPCTLPRPS1ALDH1A1MAPT
SCHEMBL31202960 0.73 PRPS1 (0.43) QPCTQPCTLPRPS1ALDH1A1MAPT
SCHEMBL6760577 0.73 NPC1 (0.51) PKMPRPS1LMNASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0410383-A1 Silver halide photographic material having improved keeping quality KONICA CORPORATION (JP) 1991-01-30 EP disclosed