Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.36 |
| ▸ | TTR | P02766 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15821727 | 0.87 | CYP1A2 (0.38) | CYP1A2GPR35TTRNPC1RAB9A | |
| SCHEMBL11335559 | 0.84 | CYP1A2 (0.46) | CYP1A2GPR35TTRNPC1RAB9A | |
| SCHEMBL74507 | 0.78 | ALDH1A1 (0.47) | CYP1A2NPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL9843745 | 0.76 | ALDH1A1 (0.38) | SMN1; SMN2HSD17B10HPGDALDH1A1KDM4E | |
| SCHEMBL4574940 | 0.73 | NPC1 (0.36) | CYP1A2NPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL28137300 | 0.72 | CYP1A2 (0.43) | CYP1A2GPR35TTRNPC1RAB9A | |
| SCHEMBL9843715 | 0.71 | CYP19A1 (0.34) | — | |
| SCHEMBL11344952 | 0.70 | MCL1 (0.50) | CYP1A2GPR35TTRNPC1RAB9A | |
| SCHEMBL496639 | 0.70 | EDNRA (0.45) | CYP1A2GPR35TTRNPC1RAB9A | |
| SCHEMBL73469 | 0.70 | PDE4A (0.41) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445073-A1 | Benzofurans | CIBA-GEIGY AG (CH) | 1991-09-04 | — | — | EP | disclosed |