SCHEMBL9843786

SCHEMBL9843786

CCCC(c1ccccc1)C(CC)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HKDC1 Q2TB90 1/20 0.55
LMNA P02545 3/20 0.46
ESR1 P03372 1/20 0.46
CYP1A2 P05177 1/20 0.46
PGR P06401 1/20 0.46
CHRM2 P08172 1/20 0.46
CYP3A4 P08684 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
AR P10275 1/20 0.46
CYP2D6 P10635 1/20 0.46
MAPT P10636 1/20 0.46
CHRM1 P11229 1/20 0.46
CYP2C9 P11712 1/20 0.46
ALOX15 P16050 1/20 0.46
DRD1 P21728 1/20 0.46
TBXA2R P21731 1/20 0.46
PTGS1 P23219 1/20 0.46
SLC6A2 P23975 1/20 0.46
CYP2C19 P33261 1/20 0.46
ADRA1A P35348 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8157573 0.93 AOC3 (0.48) HKDC1LMNASLC6A2SLC6A3AOC3
SCHEMBL4071581 0.88 HKDC1 (0.65) HKDC1LMNAESR1CYP1A2PGR
SCHEMBL2353781 0.87 HKDC1 (0.52) HKDC1LMNAESR1CYP1A2PGR
SCHEMBL28233426 0.84 HKDC1 (0.49) HKDC1LMNAESR1CYP1A2PGR
SCHEMBL12803686 0.83 TAAR1 (0.45) HKDC1LMNACYP1A2CHRM2CYP3A4
SCHEMBL7511093 0.82 TAAR1 (0.59) HKDC1LMNACYP1A2CHRM2CYP3A4
SCHEMBL7511084 0.82 TAAR1 (0.59) HKDC1LMNACYP1A2CHRM2CYP3A4
SCHEMBL28973920 0.81 LMNA (0.52) HKDC1LMNACHRM2CYP3A4CYP2D6
SCHEMBL6543318 0.81 AOC3 (0.44) HKDC1LMNASLC6A2SLC6A3AOC3
SCHEMBL5391517 0.81 HKDC1 (0.46) HKDC1LMNAESR1CYP1A2PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109456611-A A kind of degradable dinner set and preparation method thereof 杭州光启医疗科技发展有限公司 2019-03-12 CN claimed
EP-0427173-A2 Self-extinguishing polymeric compositions ENICHEM S.p.A. (IT) 1991-05-15 EP disclosed
EP-0407832-A2 Reinforced coloured thermoplastic mouldings based on polyamides and polyphenyleneethers BASF Aktiengesellschaft (DE) 1991-01-16 EP disclosed
EP-0400418-A1 Thermoplastic mouldings based on polyamide and polyphenylenether BASF Aktiengesellschaft (DE) 1990-12-05 EP disclosed
EP-0290753-A1 Process for preparing polymer beads from water-soluble ethylenically unsatarated monomers BASF Aktiengesellschaft (DE) 1988-11-17 EP disclosed
EP-0065160-A2 Self extinguishing polyolefinic compositions Montedison S.p.A. (IT) 1982-11-24 EP disclosed