Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.61 |
| ▸ | PDE4A | P27815 | 2/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.51 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844258 | 0.87 | PDE4A (0.69) | PPARGPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9851543 | 0.87 | AGTR1 (0.66) | PPARGPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9843785 | 0.86 | PDE4A (0.70) | PPARGPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9197325 | 0.83 | PPARG (0.88) | PPARGAGTR1AGTR2 | |
| Hydrochloric Acid SCHEMBL6014139 | 0.82 | PDE4A (0.70) | PDE4APDE4BPDE4CPDE4DAGTR1 | |
| SCHEMBL9851483 | 0.82 | PPARG (0.67) | PPARGPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9843803 | 0.82 | PPARG (0.58) | PPARGAGTR1ACHE | |
| SCHEMBL9843820 | 0.81 | PPARG (0.57) | PPARGAGTR1ACHE | |
| SCHEMBL9853637 | 0.81 | PPARG (0.74) | PPARGPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9844138 | 0.81 | AGTR1 (0.56) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407342-A2 | Pyrimidine derivatives | CIBA-GEIGY AG (CH) | 1991-01-09 | — | — | EP | disclosed |