Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9843838 | 0.91 | ALDH1A1 (0.60) | ALDH1A1LMNACA2CA1CA5A | |
| SCHEMBL4880583 | 0.81 | CA1 (0.58) | ALDH1A1LMNACA2CA1CA5A | |
| SCHEMBL5734169 | 0.81 | ALDH1A1 (0.64) | ALDH1A1LMNACA2CA1CA5A | |
| SCHEMBL10360804 | 0.81 | ALDH1A1 (0.77) | ALDH1A1LMNACA2CA1CA5A | |
| SCHEMBL28280178 | 0.80 | ALDH1A1 (0.62) | ALDH1A1LMNACA2CA1CA5A | |
| SCHEMBL383349 | 0.80 | ALDH1A1 (0.66) | ALDH1A1LMNACA2CA1CA5A | |
| SCHEMBL1789262 | 0.80 | ALDH1A1 (0.66) | ALDH1A1LMNATSHRCFTRHSD17B10 | |
| SCHEMBL3558813 | 0.79 | ALDH1A1 (0.62) | ALDH1A1LMNACA2CA1CA5A | |
| SCHEMBL385826 | 0.78 | ALDH1A1 (0.64) | ALDH1A1LMNATSHRCFTRHSD17B10 | |
| SCHEMBL6621914 | 0.78 | ALDH1A1 (0.64) | ALDH1A1LMNACA2CA1CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447645-A1 | Aralkylesulfonyl ureas | BAYER AG (DE) | 1991-09-25 | — | — | EP | disclosed |