Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9843840 | 0.91 | ALDH1A1 (0.57) | ALDH1A1LMNACA1CA2CA5A | |
| SCHEMBL10360804 | 0.87 | ALDH1A1 (0.77) | ALDH1A1LMNACA1CA2CA5A | |
| SCHEMBL4880583 | 0.84 | CA1 (0.58) | ALDH1A1LMNACA1CA2CA5A | |
| SCHEMBL668702 | 0.80 | ALDH1A1 (0.47) | ALDH1A1CA1CA2CA5ACA9 | |
| SCHEMBL4739142 | 0.80 | ALDH1A1 (0.68) | ALDH1A1LMNACA1CA2CA5A | |
| Hydrochloric Acid SCHEMBL4443950 | 0.79 | ALDH1A1 (0.66) | ALDH1A1LMNACA1CA2CA5A | |
| SCHEMBL31123666 | 0.79 | ALDH1A1 (0.66) | ALDH1A1LMNATSHRKMT2AHIF1A | |
| SCHEMBL4068457 | 0.79 | ALDH1A1 (0.66) | ALDH1A1LMNATSHRKMT2AHIF1A | |
| SCHEMBL16672908 | 0.79 | ALDH1A1 (0.66) | ALDH1A1LMNATSHRCFTRHSD17B10 | |
| SCHEMBL1629682 | 0.78 | ALDH1A1 (0.70) | ALDH1A1LMNACA1CA2CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447645-A1 | Aralkylesulfonyl ureas | BAYER AG (DE) | 1991-09-25 | — | — | EP | disclosed |