Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA5A | P35218 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | CFTR | P13569 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15461583 | 0.85 | ALDH1A1 (0.57) | CA1CA2CA5ACA9ALDH1A1 | |
| SCHEMBL7363401 | 0.85 | ALDH1A1 (0.57) | CA1CA2CA5ACA9ALDH1A1 | |
| SCHEMBL9843838 | 0.84 | ALDH1A1 (0.60) | CA1CA2CA5ACA9ALDH1A1 | |
| SCHEMBL8435579 | 0.84 | TSHR (0.61) | CA1CA2CA9ALDH1A1LMNA | |
| SCHEMBL2884550 | 0.83 | ALDH1A1 (0.55) | CA1CA2CA5ACA9ALDH1A1 | |
| SCHEMBL9843840 | 0.81 | ALDH1A1 (0.57) | CA1CA2CA5ACA9ALDH1A1 | |
| SCHEMBL10438447 | 0.81 | CA1 (0.44) | CA1CA2CA5ACA9ALDH1A1 | |
| SCHEMBL4912518 | 0.81 | ALDH1A1 (0.53) | CA1CA2CA5ACA9ALDH1A1 | |
| SCHEMBL646787 | 0.81 | L3MBTL1 (0.54) | CA1CA2CA5ACA9ALDH1A1 | |
| SCHEMBL10680197 | 0.80 | KMT2A (0.45) | CA1CA2CA5ACA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1171197-A | Method for synthesizing herbicide of sulfonylureas | ZHANG HUIMING (CN) | 1998-01-28 | — | — | CN | claimed |
| US-H890-H | Herbicidal heterocyclicbenzylsulfonamides | Rorer, Morris P. (US) | 1991-02-05 | — | — | US | claimed |
| JP-1221366-A | — | — | None | — | — | JP | disclosed |
| EP-4276092-A1 | COMPOUND LIBRARY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-15 | — | — | EP | disclosed |
| US-11773058-B2 | Sulfonamide carboxamide compounds | INFLAZOME LIMITED (IE) | 2023-10-03 | — | — | US | disclosed |
| US-11773058-B2 | Sulfonamide carboxamide compounds | INFLAZOME LIMITED (IE) | 2023-10-03 | — | — | US | disclosed |
| US-11773058-B2 | Sulfonamide carboxamide compounds | INFLAZOME LIMITED (IE) | 2023-10-03 | — | — | US | disclosed |
| CN-116783160-A | Libraries of compounds | 中外制药株式会社 | 2023-09-19 | — | — | CN | disclosed |
| EP-3880666-B1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS AG (CH) | 2023-06-28 | — | — | EP | disclosed |
| US-20230024859-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS AG (CH) | 2023-01-26 | — | — | US | disclosed |
| US-11518739-B2 | Sulfonamide carboxamide compounds | INFLAZOME LIMITED (IE) | 2022-12-06 | — | — | US | disclosed |
| US-5053072-A | HETEROCYCLIC N-ACYLSULFONAMIDES, AND THEIR USE AS HERBICIDES OR GROWTH REGULATORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-01 | — | — | US | disclosed |
| US-H890-H | Herbicidal heterocyclicbenzylsulfonamides | Rorer, Morris P. (US) | 1991-02-05 | — | — | US | disclosed |
| EP-0353640-A2 | Heterocyclic N-acylsulphonamides, process for their preparation, agents containing them and their use as herbicides and plant growth regulators | Hoechst Schering AgrEvo GmbH (DE) | 1990-02-07 | — | — | EP | disclosed |
| US-4897105-A | (1,2,4)-THIADIAZOLO(2,3-A)PYRIMIDINE DERIVATIVES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-01-30 | — | — | US | disclosed |
| JP-H01221366-A | PRODUCTION OF SULFONYLUREA DERIVATIVE | TAKEDA CHEM IND LTD | 1989-09-04 | — | — | JP | disclosed |
| CN-87102275-A | Selective herbicide and manufacturing thereof and use | — | 1988-02-17 | — | — | CN | disclosed |
| US-4699649-A | Herbicidal heterocyclicbenzylsulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-10-13 | — | — | US | disclosed |
| EP-0239064-A2 | Herbicidal compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-09-30 | — | — | EP | disclosed |
| EP-0164268-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230024859-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NLRP1, NLRP3, NOD1 | CA1 3841/4885CA2 1348/4885CA5A 1703/4885 |
| US-11773058-B2 | Sulfonamide carboxamide compounds | NLRP3, NOD1, NLRP1 | CA1 2065/4885CA2 1651/4885CA5A 1120/4885 |
| US-11518739-B2 | Sulfonamide carboxamide compounds | NLRP3, PYCARD, NOD1 | CA1 2278/4885CA2 1228/4885CA5A 646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.