Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.65 |
| ▸ | GRM2 | Q14416 | 7/20 | 0.47 |
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844486 | 0.89 | SIGMAR1 (0.83) | SIGMAR1GRM2 | |
| SCHEMBL9844032 | 0.85 | SIGMAR1 (0.65) | SIGMAR1GRM2OPRL1 | |
| SCHEMBL9844231 | 0.81 | SIGMAR1 (0.63) | SIGMAR1GRM2CCR1OPRM1OPRL1 | |
| SCHEMBL9844261 | 0.81 | SIGMAR1 (0.63) | SIGMAR1GRM2 | |
| SCHEMBL9844304 | 0.79 | GRM2 (0.54) | SIGMAR1GRM2OPRM1 | |
| SCHEMBL9844106 | 0.79 | SIGMAR1 (0.63) | SIGMAR1GRM2 | |
| SCHEMBL9844264 | 0.79 | SIGMAR1 (0.63) | SIGMAR1GRM2CCR1OPRM1OPRL1 | |
| SCHEMBL9844324 | 0.78 | SIGMAR1 (0.76) | SIGMAR1GRM2 | |
| SCHEMBL7290651 | 0.77 | SIGMAR1 (0.83) | SIGMAR1 | |
| SCHEMBL9742163 | 0.77 | GRM2 (0.61) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |