Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 8/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9676924 | 0.89 | SIGMAR1 (0.60) | GRM2SIGMAR1 | |
| SCHEMBL9844032 | 0.84 | SIGMAR1 (0.65) | GRM2SIGMAR1 | |
| SCHEMBL9844261 | 0.80 | SIGMAR1 (0.63) | GRM2SIGMAR1 | |
| SCHEMBL9844231 | 0.80 | SIGMAR1 (0.63) | GRM2SIGMAR1OPRM1 | |
| SCHEMBL9742163 | 0.80 | GRM2 (0.61) | GRM2HTR7 | |
| SCHEMBL9844017 | 0.79 | SIGMAR1 (0.65) | GRM2SIGMAR1OPRM1 | |
| SCHEMBL9844101 | 0.79 | GRM2 (0.64) | GRM2SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL9844264 | 0.78 | SIGMAR1 (0.63) | GRM2SIGMAR1OPRM1 | |
| SCHEMBL9844106 | 0.78 | SIGMAR1 (0.63) | GRM2SIGMAR1 | |
| SCHEMBL9844324 | 0.78 | SIGMAR1 (0.76) | GRM2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |