Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.65 |
| ▸ | GRM2 | Q14416 | 6/20 | 0.53 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844231 | 0.93 | SIGMAR1 (0.63) | SIGMAR1GRM2OPRL1 | |
| SCHEMBL9844261 | 0.93 | SIGMAR1 (0.63) | SIGMAR1GRM2 | |
| SCHEMBL9844106 | 0.93 | SIGMAR1 (0.63) | SIGMAR1GRM2 | |
| SCHEMBL9844264 | 0.93 | SIGMAR1 (0.63) | SIGMAR1GRM2OPRL1 | |
| SCHEMBL9502924 | 0.90 | SIGMAR1 (0.82) | SIGMAR1GRM2 | |
| SCHEMBL9844046 | 0.90 | MAOA (0.57) | SIGMAR1GRM2 | |
| SCHEMBL9844324 | 0.90 | SIGMAR1 (0.76) | SIGMAR1GRM2 | |
| SCHEMBL9678242 | 0.88 | SIGMAR1 (0.80) | SIGMAR1 | |
| SCHEMBL9844085 | 0.88 | SIGMAR1 (0.68) | SIGMAR1GRM2 | |
| SCHEMBL9844060 | 0.87 | OPRM1 (0.53) | SIGMAR1GRM2OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |