Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2083327 | 0.83 | ALOX5 (0.32) | ALOX5LTB4R | |
| SCHEMBL10110370 | 0.83 | ALOX5 (0.33) | ALOX5GABRA1GABRB2 | |
| SCHEMBL28185456 | 0.79 | AKR1C3 (0.39) | ALOX5LTB4RALDH1A1HPGDTSHR | |
| SCHEMBL9631536 | 0.77 | — | — | |
| SCHEMBL20692523 | 0.76 | PDE7A (0.32) | ALOX5 | |
| SCHEMBL11383379 | 0.74 | FFAR2 (0.33) | ALOX5ALDH1A1RAB9ANPC1HPGD | |
| Hydrochloric Acid SCHEMBL10919944 | 0.74 | LMNA (0.35) | ALOX5LTB4RALDH1A1RAB9ANPC1 | |
| SCHEMBL5097717 | 0.71 | ALOX5 (0.34) | ALOX5 | |
| SCHEMBL18003233 | 0.70 | — | — | |
| SCHEMBL13723850 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0459230-A1 | Methanthiols, process for their preparation and their use | HAARMANN & REIMER GMBH (DE) | 1991-12-04 | — | — | EP | disclosed |