Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 5/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | CCR3 | P51677 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678329 | 0.90 | GRM2 (0.58) | GRM2HTR1ASLC6A4CCR3GAA | |
| SCHEMBL9844291 | 0.90 | GRM2 (0.55) | GRM2 | |
| SCHEMBL9844422 | 0.90 | GRM2 (0.55) | GRM2HTR1ASLC6A4CCR3HTR2A | |
| Hydrochloric Acid SCHEMBL9844260 | 0.90 | GRM2 (0.54) | GRM2 | |
| SCHEMBL9844119 | 0.89 | GRM2 (0.56) | GRM2SLC6A4 | |
| SCHEMBL9844101 | 0.88 | GRM2 (0.64) | GRM2SLC6A4CCR3 | |
| SCHEMBL9844448 | 0.88 | ABCB1 (0.55) | GRM2SLC6A4 | |
| SCHEMBL9844426 | 0.84 | GRM2 (0.52) | GRM2HTR1ASLC6A4CCR3HTR2A | |
| SCHEMBL6416989 | 0.84 | HTR1A (0.60) | GRM2HTR1ASLC6A4 | |
| SCHEMBL9844336 | 0.83 | GRM2 (0.56) | GRM2HTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |