Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9844260 | 0.99 | GRM2 (0.54) | GRM2SIGMAR1GRIN1GRIN2BOPRM1 | |
| SCHEMBL9844084 | 0.90 | GRM2 (0.57) | GRM2 | |
| SCHEMBL9678853 | 0.90 | SIGMAR1 (0.65) | GRM2SIGMAR1GRIN1GRIN2B | |
| SCHEMBL9844101 | 0.90 | GRM2 (0.64) | GRM2SIGMAR1 | |
| SCHEMBL9844290 | 0.90 | GRM2 (0.53) | GRM2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL10389069 | 0.89 | SIGMAR1 (0.64) | GRM2SIGMAR1GRIN1GRIN2B | |
| SCHEMBL9844448 | 0.88 | ABCB1 (0.55) | GRM2 | |
| SCHEMBL9844385 | 0.87 | SLC6A2 (0.58) | GRM2 | |
| SCHEMBL9844211 | 0.87 | GRM2 (0.55) | GRM2OPRM1 | |
| SCHEMBL9844131 | 0.87 | GRM2 (0.55) | GRM2GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |