Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 6/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678765 | 0.91 | GRM2 (0.56) | GRM2KDM4EKDM2BHSD11B1MGLL | |
| SCHEMBL9844329 | 0.91 | SIGMAR1 (0.54) | GRM2KDM4EKCNH2HTR2A | |
| SCHEMBL9844308 | 0.89 | MAOA (0.56) | GRM2HSD11B1KCNH2HTR2A | |
| SCHEMBL9844499 | 0.88 | HTR2A (0.53) | GRM2KCNH2HTR2A | |
| SCHEMBL9844433 | 0.88 | SIGMAR1 (0.45) | GRM2KDM2BKCNH2HTR2A | |
| SCHEMBL9844338 | 0.85 | GRM2 (0.51) | GRM2HSD11B1MGLLKCNH2HTR2A | |
| SCHEMBL9844167 | 0.83 | HTR7 (0.46) | HTR7KCNH2HTR2A | |
| SCHEMBL9844084 | 0.83 | GRM2 (0.57) | GRM2HTR7HTR2A | |
| SCHEMBL9844242 | 0.82 | HTR2A (0.52) | GRM2KDM4EHTR7HTR2A | |
| SCHEMBL9844055 | 0.82 | GRM2 (0.49) | GRM2HTR7MGLLKCNH2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |