Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | F7 | P08709 | 1/20 | 0.49 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.48 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.48 |
| ▸ | MDM4 | O15151 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9754281 | 0.84 | TSHR (0.62) | TSHRKMT2AALDH1A1HPGDLMNA | |
| SCHEMBL22525971 | 0.84 | NPSR1 (0.55) | TSHRKMT2AALDH1A1HPGDLMNA | |
| SCHEMBL27935595 | 0.84 | NPSR1 (0.55) | TSHRKMT2AALDH1A1HPGDLMNA | |
| SCHEMBL4184595 | 0.82 | TSHR (0.61) | TSHRKMT2AALDH1A1HPGDLMNA | |
| SCHEMBL5672188 | 0.81 | MAPT (0.61) | KMT2AALDH1A1HPGDL3MBTL1MEN1 | |
| SCHEMBL28845306 | 0.81 | TSHR (0.64) | TSHRKMT2AALDH1A1HPGDLMNA | |
| SCHEMBL5834057 | 0.80 | TSHR (0.62) | TSHRKMT2AALDH1A1HPGDLMNA | |
| SCHEMBL7391210 | 0.80 | TSHR (0.54) | TSHRKMT2AALDH1A1HPGDLMNA | |
| SCHEMBL1386996 | 0.79 | LMNA (0.79) | TSHRKMT2AALDH1A1HPGDLMNA | |
| SCHEMBL6289427 | 0.78 | TSHR (0.61) | TSHRKMT2AALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433662-A2 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-26 | — | — | EP | claimed |