Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | CTSC | P53634 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.49 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.49 |
| ▸ | MDM4 | O15151 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4001999 | 0.90 | SLC6A9 (0.63) | TSHRKMT2AALDH1A1HPGDLMNA | |
| SCHEMBL2010681 | 0.90 | LMNA (0.69) | TSHRKMT2AALDH1A1HPGDL3MBTL1 | |
| Hydrochloric Acid SCHEMBL2010289 | 0.88 | SLC6A9 (0.62) | TSHRKMT2AALDH1A1HPGDLMNA | |
| Hydrochloric Acid SCHEMBL2008550 | 0.88 | LMNA (0.67) | TSHRKMT2AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL7369365 | 0.88 | SLC6A9 (0.59) | TSHRKMT2AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL8212646 | 0.86 | KDM4E (0.57) | TSHRKMT2AALDH1A1HPGDMEN1 | |
| Hydrochloric Acid SCHEMBL2007082 | 0.84 | KDM4E (0.56) | TSHRKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL16935767 | 0.82 | CTSC (0.49) | TSHRLMNACTSCGAA | |
| SCHEMBL21331608 | 0.82 | CTSC (0.53) | TSHRALDH1A1LMNACTSCMAPT | |
| SCHEMBL9844158 | 0.82 | TSHR (0.59) | TSHRKMT2AALDH1A1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722919-B2 | Process for production of mono-substituted alkylated compound using aldimine or derivative thereof | NAGASE & CO., LTD. (JP) | 2014-05-13 | — | — | US | disclosed |
| US-8722919-B2 | Process for production of mono-substituted alkylated compound using aldimine or derivative thereof | NAGASE & CO., LTD. (JP) | 2014-05-13 | — | — | US | disclosed |
| US-20090054679-A1 | PROCESS FOR PRODUCTION OF MONO-SUBSTITUTED ALKYLATED COMPOUND USING ALDIMINE OR DERIVATIVE THEREOF | NAGASE & CO., LTD. (JP) | 2009-02-26 | — | — | US | disclosed |
| US-20090054679-A1 | PROCESS FOR PRODUCTION OF MONO-SUBSTITUTED ALKYLATED COMPOUND USING ALDIMINE OR DERIVATIVE THEREOF | NAGASE & CO., LTD. (JP) | 2009-02-26 | — | — | US | disclosed |
| EP-1930315-A1 | PROCESS FOR PRODUCTION OF MONO-SUBSTITUTED ALKYLATED COMPOUND USING ALDIMINE OR DERIVATIVE THEREOF | NAGASE & COMPANY, LTD. (JP) | 2008-06-11 | — | — | EP | disclosed |
| EP-0777680-B1 | UROKINASE RECEPTOR LIGANDS | CHIRON CORP (US) | 2002-03-20 | — | — | EP | disclosed |
| WO-1994027958-A1 | 4-AMIDINOPHENYLSULPHONAMIDES FOR THE TREATMENT OF THROMBO-EMBOLITIC CONDITIONS | BOEHRINGER MANNHEIM GMBH (DE) | 1994-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054679-A1 | PROCESS FOR PRODUCTION OF MONO-SUBSTITUTED ALKYLATED COMPOUND USING ALDIMINE OR DERIVATIVE THEREOF | AADAT, BCAT2, BCAT1 | TSHR 4219/4885KMT2A 237/4885ALDH1A1 131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.