Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 3/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678999 | 0.91 | GRM2 (0.43) | GRM2SLC6A2SLC6A4OPRM1SIGMAR1 | |
| SCHEMBL9844402 | 0.86 | GRM2 (0.44) | GRM2SIGMAR1 | |
| SCHEMBL9844288 | 0.85 | GRM2 (0.53) | GRM2SIGMAR1 | |
| SCHEMBL9844079 | 0.84 | GRM2 (0.60) | GRM2 | |
| SCHEMBL9844097 | 0.84 | GRM2 (0.55) | GRM2 | |
| SCHEMBL9844082 | 0.82 | SLC6A2 (0.60) | SLC6A2SLC6A4HTR7SIGMAR1 | |
| SCHEMBL9844356 | 0.82 | GRM2 (0.52) | GRM2 | |
| SCHEMBL9844023 | 0.81 | SLC6A2 (0.48) | GRM2SLC6A2SLC6A4HTR7TMEM97 | |
| SCHEMBL9844255 | 0.80 | GRM2 (0.52) | GRM2SLC6A2SLC6A4 | |
| SCHEMBL9844274 | 0.80 | GRM2 (0.53) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |