Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678759 | 0.90 | SLC6A2 (0.57) | SLC6A2SLC6A4MEN1KMT2AKDM4E | |
| SCHEMBL9844023 | 0.90 | SLC6A2 (0.48) | SLC6A2SLC6A4MEN1KMT2AKDM4E | |
| SCHEMBL9844448 | 0.86 | ABCB1 (0.55) | SLC6A2SLC6A4MEN1KMT2AKDM4E | |
| SCHEMBL9844291 | 0.84 | GRM2 (0.55) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9844260 | 0.83 | GRM2 (0.54) | SIGMAR1 | |
| SCHEMBL9844101 | 0.83 | GRM2 (0.64) | SLC6A2SLC6A4SIGMAR1PRMT3CARM1 | |
| SCHEMBL9844167 | 0.83 | HTR7 (0.46) | KMT2AHTR7CYP2C19 | |
| SCHEMBL9844084 | 0.83 | GRM2 (0.57) | SLC6A4HTR7 | |
| SCHEMBL9844243 | 0.82 | GRM2 (0.42) | SLC6A2SLC6A4HTR7SIGMAR1 | |
| SCHEMBL9676935 | 0.82 | SLC6A2 (0.47) | SLC6A2SLC6A4MEN1KMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |