Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844414 | 0.88 | SOAT1 (0.58) | SOAT1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7829260 | 0.83 | SOAT1 (0.63) | SOAT1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9504118 | 0.80 | LMNA (0.58) | KMT2A | |
| SCHEMBL9679362 | 0.80 | KMT2A (0.63) | SOAT1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6270943 | 0.77 | SOAT1 (0.63) | SOAT1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9678560 | 0.77 | SOAT1 (0.63) | SOAT1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL17690718 | 0.77 | NPSR1 (0.57) | MEN1KMT2A | |
| SCHEMBL9723518 | 0.77 | LMNA (0.54) | KMT2A | |
| SCHEMBL9844424 | 0.77 | NPSR1 (0.56) | MEN1KMT2A | |
| SCHEMBL6273697 | 0.76 | SOAT1 (0.61) | SOAT1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433662-A2 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-26 | — | — | EP | disclosed |