Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678785 | 0.91 | GRM2 (0.52) | GRM2SIGMAR1CARM1PRMT6CHRM4 | |
| SCHEMBL9844426 | 0.90 | GRM2 (0.52) | GRM2SIGMAR1CHRM4DRD2HTR1A | |
| SCHEMBL9844478 | 0.88 | GRM2 (0.60) | GRM2CARM1PRMT6HTR7SLC6A2 | |
| SCHEMBL9844072 | 0.86 | GRM2 (0.53) | GRM2CARM1PRMT6HTR7 | |
| SCHEMBL9844422 | 0.85 | GRM2 (0.55) | GRM2CARM1PRMT6HTR1AHTR2A | |
| SCHEMBL9844281 | 0.83 | GRM2 (0.52) | GRM2SIGMAR1CARM1PRMT6HTR2A | |
| SCHEMBL9676146 | 0.83 | GRM2 (0.54) | GRM2SIGMAR1CHRM4HTR1ASLC6A2 | |
| SCHEMBL9844472 | 0.82 | GRM2 (0.50) | GRM2SIGMAR1DRD2DRD3NOTUM | |
| SCHEMBL9844088 | 0.82 | GRM2 (0.52) | GRM2SIGMAR1CARM1PRMT6HTR7 | |
| SCHEMBL9844309 | 0.81 | CARM1 (0.45) | GRM2SIGMAR1CARM1PRMT6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |