Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 7/20 | 0.52 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | FADS1 | O60427 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844478 | 0.93 | GRM2 (0.60) | GRM2CARM1PRMT6BCHE | |
| SCHEMBL9844088 | 0.90 | GRM2 (0.52) | GRM2CARM1PRMT6ALDH1A1BCHE | |
| SCHEMBL9677077 | 0.90 | GRM2 (0.54) | GRM2CARM1PRMT6KDM4EALDH1A1 | |
| SCHEMBL9844211 | 0.89 | GRM2 (0.55) | GRM2KDM4EALDH1A1MAPTCCR3 | |
| SCHEMBL9844290 | 0.88 | GRM2 (0.53) | GRM2CARM1PRMT6CCR3SIGMAR1 | |
| SCHEMBL9844072 | 0.84 | GRM2 (0.53) | GRM2CARM1PRMT6MAPT | |
| SCHEMBL9844267 | 0.83 | GRM2 (0.50) | GRM2CARM1PRMT6SIGMAR1HTR2A | |
| SCHEMBL9844309 | 0.83 | CARM1 (0.45) | GRM2CARM1PRMT6KDM4EALDH1A1 | |
| SCHEMBL9844422 | 0.82 | GRM2 (0.55) | GRM2CARM1PRMT6CCR3HTR2A | |
| SCHEMBL9678427 | 0.82 | GRM2 (0.63) | GRM2CARM1PRMT6SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |