Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9676125 | 0.91 | SIGMAR1 (0.51) | CARM1PRMT6GRM2SIGMAR1ABCB1 | |
| SCHEMBL9844448 | 0.90 | ABCB1 (0.55) | GRM2ABCB1KDM4EMEN1ALDH1A1 | |
| SCHEMBL9844422 | 0.89 | GRM2 (0.55) | CARM1PRMT6GRM2HTR2ACCR3 | |
| SCHEMBL9844290 | 0.88 | GRM2 (0.53) | CARM1PRMT6GRM2SIGMAR1HTR2A | |
| SCHEMBL9844023 | 0.86 | SLC6A2 (0.48) | CARM1PRMT6GRM2SIGMAR1HTR2A | |
| SCHEMBL9844478 | 0.86 | GRM2 (0.60) | CARM1PRMT6GRM2 | |
| SCHEMBL9844072 | 0.85 | GRM2 (0.53) | CARM1PRMT6GRM2MEN1KMT2A | |
| SCHEMBL9844088 | 0.83 | GRM2 (0.52) | CARM1PRMT6GRM2SIGMAR1ALDH1A1 | |
| SCHEMBL9844281 | 0.83 | GRM2 (0.52) | CARM1PRMT6GRM2SIGMAR1HTR2A | |
| SCHEMBL9678951 | 0.83 | SIGMAR1 (0.54) | GRM2SIGMAR1ABCB1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |