Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844335 | 0.78 | GAA (0.49) | NR1I2HSD11B1GAAMAPTTP53 | |
| SCHEMBL9844092 | 0.77 | HSD11B1 (0.54) | NR1I2HSD11B1GAAALDH1A1NPC1 | |
| SCHEMBL9844298 | 0.74 | PDE2A (0.47) | NR1I2HSD11B1GAAPOLBALDH1A1 | |
| SCHEMBL9844107 | 0.73 | ALDH1A1 (0.53) | NR1I2HSD11B1GAAMAPTTP53 | |
| SCHEMBL10179020 | 0.71 | NR1I2 (0.46) | NR1I2HSD11B1GAAMAPTTP53 | |
| SCHEMBL2747352 | 0.71 | HSD11B1 (0.55) | HSD11B1GAAMAPTTP53ALDH1A1 | |
| SCHEMBL9691041 | 0.71 | RAB9A (0.36) | HSD11B1GAAMAPTTP53POLB | |
| SCHEMBL9844367 | 0.70 | KDM4E (0.50) | NR1I2HSD11B1GAAMAPTTP53 | |
| SCHEMBL19663187 | 0.70 | RAB9A (0.68) | GAAMAPTTP53ALDH1A1NPC1 | |
| SCHEMBL9844105 | 0.69 | KDM4E (0.57) | NR1I2HSD11B1GAAMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441718-A1 | Herbicidally active triazolopyridine compounds | RHONE-POULENC AGROCHIMIE (FR) | 1991-08-14 | — | — | EP | disclosed |