Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.42 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844000 | 0.84 | SLC6A3 (0.42) | SLC6A3DRD2SLC6A2GRIN2BHDAC3 | |
| SCHEMBL270517 | 0.83 | HDAC3 (0.43) | SLC6A3DRD2SLC6A2GRIN2BHDAC3 | |
| SCHEMBL1046197 | 0.78 | SLC6A3 (0.47) | SLC6A3DRD2SLC6A2GRIN2BHDAC3 | |
| SCHEMBL9844357 | 0.77 | TNF (0.39) | SLC6A3SLC6A2MGLLSLC6A4CYP2D6 | |
| SCHEMBL9210581 | 0.77 | RORC (0.42) | SLC6A3DRD2SLC6A2GRIN2BHDAC3 | |
| SCHEMBL9843859 | 0.75 | SLC6A3 (0.43) | SLC6A3DRD2SLC6A2GRIN2BHDAC3 | |
| SCHEMBL2879865 | 0.75 | IDO1 (0.44) | SLC6A3SLC6A2HDAC1SLC6A4CYP2D6 | |
| SCHEMBL23881813 | 0.74 | SLC6A3 (0.48) | SLC6A3DRD2SLC6A2GRIN2BHDAC3 | |
| SCHEMBL1299443 | 0.74 | TAAR1 (0.58) | SLC6A3DRD2SLC6A2GRIN2BGRIN1 | |
| SCHEMBL1046199 | 0.74 | SLC6A3 (0.47) | SLC6A3DRD2SLC6A2GRIN2BHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447645-A1 | Aralkylesulfonyl ureas | BAYER AG (DE) | 1991-09-25 | — | — | EP | disclosed |