Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3593144 | 0.81 | CA12 (0.54) | CA12CA1CA2CA5ACA9 | |
| SCHEMBL3171854 | 0.81 | TAAR1 (0.41) | CA12CA1CA2CA5ACA9 | |
| SCHEMBL2091568 | 0.80 | SLC6A3 (0.49) | SLC6A3DRD2SLC6A2SLC6A4EPHX2 | |
| SCHEMBL20303425 | 0.80 | ALPL (0.36) | SLC6A3SLC6A4EPHX2 | |
| SCHEMBL20303379 | 0.80 | CNR2 (0.38) | SLC6A3SLC6A4RORC | |
| SCHEMBL1960375 | 0.80 | KDM4E (0.46) | CA12CA1CA2CA5ACA9 | |
| SCHEMBL9016848 | 0.78 | NPSR1 (0.50) | SLC6A3SLC6A2SLC6A4HDAC1CYP2D6 | |
| SCHEMBL4860922 | 0.78 | L3MBTL1 (0.56) | — | |
| SCHEMBL2376083 | 0.78 | HCRTR1 (0.41) | SLC6A3DRD2SLC6A2SLC6A4HDAC3 | |
| SCHEMBL5657713 | 0.77 | L3MBTL1 (0.46) | SLC6A3SLC6A2SLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447645-A1 | Aralkylesulfonyl ureas | BAYER AG (DE) | 1991-09-25 | — | — | EP | disclosed |