Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.58 |
| ▸ | GRM2 | Q14416 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844101 | 0.92 | GRM2 (0.64) | SLC6A2SLC6A4GRM2CCR3PRMT3 | |
| SCHEMBL9844211 | 0.90 | GRM2 (0.55) | SLC6A2SLC6A4GRM2ALDH1A1SLC6A3 | |
| SCHEMBL9844131 | 0.90 | GRM2 (0.55) | SLC6A2SLC6A4GRM2CCR3 | |
| SCHEMBL9677253 | 0.89 | GRM2 (0.57) | SLC6A2SLC6A4GRM2ALDH1A1CCR3 | |
| SCHEMBL7529065 | 0.89 | GRM2 (0.57) | SLC6A2SLC6A4GRM2ALDH1A1CCR3 | |
| SCHEMBL9844088 | 0.89 | GRM2 (0.52) | SLC6A2SLC6A4GRM2ALDH1A1CARM1 | |
| SCHEMBL9844291 | 0.87 | GRM2 (0.55) | GRM2 | |
| Hydrochloric Acid SCHEMBL9844260 | 0.86 | GRM2 (0.54) | GRM2 | |
| SCHEMBL9844119 | 0.83 | GRM2 (0.56) | SLC6A2SLC6A4GRM2 | |
| SCHEMBL9844448 | 0.82 | ABCB1 (0.55) | SLC6A2SLC6A4GRM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |