SCHEMBL9844392

SCHEMBL9844392

C=CS(=O)(=O)c1ccc2cc(N)ccc2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.48
HSD17B10 Q99714 5/20 0.48
TSHR P16473 5/20 0.48
LMNA P02545 3/20 0.48
MAPT P10636 2/20 0.48
NPC1 O15118 1/20 0.48
TP53 P04637 1/20 0.48
XBP1 P17861 1/20 0.48
MAPK1 P28482 1/20 0.48
HTT P42858 1/20 0.48
RAB9A P51151 1/20 0.48
MDM2 Q00987 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
NT5E P21589 2/20 0.44
CASP6 P55212 2/20 0.44
NSD2 O96028 1/20 0.44
DUSP3 P51452 1/20 0.44
PTPN5 P54829 1/20 0.44
PTPN11 Q06124 1/20 0.44
CYP3A4 P08684 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11330621 0.81 LMNA (0.57) ALDH1A1HSD17B10TSHRLMNAMAPT
SCHEMBL1374724 0.80 TSHR (0.59) ALDH1A1HSD17B10TSHRLMNAMAPT
SCHEMBL29670171 0.79 NT5E (0.66) ALDH1A1HSD17B10TSHRLMNAMAPT
SCHEMBL158630 0.79 NT5E (0.66) ALDH1A1HSD17B10TSHRLMNAMAPT
SCHEMBL947445 0.78 ALDH1A1 (0.48) ALDH1A1HSD17B10TSHRLMNAMAPT
SCHEMBL1376919 0.77 ALDH1A1 (0.62) ALDH1A1HSD17B10TSHRLMNAMAPT
SCHEMBL8784778 0.77 NT5E (0.64) ALDH1A1HSD17B10TSHRLMNAMAPT
Water SCHEMBL20296902 0.77 NT5E (0.64) ALDH1A1HSD17B10TSHRLMNAMAPT
SCHEMBL1802953 0.76 LMNA (0.67) ALDH1A1HSD17B10TSHRLMNAMAPT
SCHEMBL11021129 0.76 NT5E (0.62) ALDH1A1HSD17B10TSHRLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0433764-A1 Reactive dyestuffs with triazin- and chlorobutinyl anchor BASF Aktiengesellschaft (DE) 1991-06-26 EP disclosed