SCHEMBL1376919

SCHEMBL1376919

C=CS(=O)(=O)c1cccc(N)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.62
TSHR P16473 2/20 0.62
HSD17B10 Q99714 2/20 0.62
TDP1 Q9NUW8 1/20 0.62
LMNA P02545 2/20 0.61
CA2 P00918 4/20 0.59
CA12 O43570 3/20 0.59
CA1 P00915 3/20 0.59
CA9 Q16790 3/20 0.59
CA4 P22748 2/20 0.59
CA14 Q9ULX7 1/20 0.59
F2 P00734 3/20 0.49
PRSS1 P07477 3/20 0.49
PRSS2 P07478 3/20 0.49
PRSS3 P35030 3/20 0.49
POLB P06746 1/20 0.47
CYP19A1 P11511 1/20 0.45
PKM P14618 3/20 0.44
HTR6 P50406 1/20 0.43
NPC1 O15118 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL54845 0.85 TSHR (0.50) ALDH1A1TSHRHSD17B10TDP1LMNA
SCHEMBL4387338 0.81 TSHR (0.81) ALDH1A1TSHRHSD17B10TDP1LMNA
SCHEMBL9844392 0.77 ALDH1A1 (0.48) ALDH1A1TSHRHSD17B10TDP1LMNA
SCHEMBL29044 0.77 TSHR (1.00) ALDH1A1TSHRHSD17B10TDP1LMNA
SCHEMBL1655356 0.77 TSHR (1.00) ALDH1A1TSHRHSD17B10TDP1LMNA
SCHEMBL34546 0.76 LMNA (1.00) ALDH1A1TSHRHSD17B10TDP1LMNA
SCHEMBL29635012 0.76 LMNA (1.00) ALDH1A1TSHRHSD17B10TDP1LMNA
SCHEMBL30544199 0.76 LMNA (1.00) ALDH1A1TSHRHSD17B10TDP1LMNA
SCHEMBL5561963 0.76 LMNA (1.00) ALDH1A1TSHRHSD17B10TDP1LMNA
SCHEMBL7650936 0.76 HSD17B1 (0.42) ALDH1A1TSHRHSD17B10TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 235 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1490441-B2 DYE MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PRODUCTION AND USE DYSTAR COLOURS DISTRIB GMBH (DE) 2012-12-26 EP claimed
US-20090320217-A1 MIXTURES OF FIBRE-REACTIVE AZO DYES DYSTAR TEXTIFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2009-12-31 US claimed
EP-2118214-A2 MIXTURES OF FIBRE-REACTIVE AZO DYES DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2009-11-18 EP claimed
US-20090025152-A1 DYE MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND USE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2009-01-29 US claimed
EP-1508596-B1 Mixtures of azo reactive dyes, process for their preparation and the use thereof DYSTAR TEXTILFARBEN GMBH & CO (DE) 2009-01-28 EP claimed
CN-100434483-C Dye mixtures of fiber-reactive azo dyes, their preparation and use DYSTAR TEXTILFARBEN GMBH & CO (DE) 2008-11-19 CN claimed
EP-1490441-B1 DYE MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PRODUCTION AND USE DYSTAR TEXTILFARBEN GMBH & CO (DE) 2008-09-10 EP claimed
WO-2008095802-A2 MIXTURES OF FIBRE-REACTIVE AZO DYES DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2008-08-14 WO claimed
EP-1490442-B1 DYE MIXTURES OF FIBRE REACTIVE AZODYES, PRODUCTION AND USE THEREOF DYSTAR TEXTILFARBEN GMBH & CO (DE) 2008-03-19 EP claimed
EP-1508598-B1 Mixture of fiberreactive azo dyes process for their preparation and use DYSTAR TEXTILFARBEN GMBH & CO (DE) 2008-03-19 EP claimed
CN-1643079-A Dye mixtures of fiber-reactive azo dyes, their preparation and use DYSTAR TEXTILFARBEN GMBH & CO (DE) 2005-07-20 CN claimed
US-20050150063-A1 Fiber-reactive azo dyes, preparation thereof and use thereof DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2005-07-14 US claimed
EP-1508596-A1 Mixtures of azo reactive dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2005-02-23 EP claimed
EP-1508598-A1 Mixture of fiberreactive azo dyes process for their preparation and use DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2005-02-23 EP claimed
US-20050034252-A1 Dye mixtures of fiber-reactive azo dyes, their preparation and their use DYSTAR TEXTILFARBEN GMBH & CO. (DE) 2005-02-17 US claimed
US-20050034253-A1 Mixture; ink for ink jet printing DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2005-02-17 US claimed
EP-1499681-A1 FIBRE-REACTIVE AZO DYES, THEIR PRODUCTION AND THEIR USE DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2005-01-26 EP claimed
EP-1490442-A1 DYE MIXTURES OF FIBRE REACTIVE AZODYES, PRODUCTION AND USE THEREOF DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2004-12-29 EP claimed
WO-2003089521-A1 FIBRE-REACTIVE AZO DYES, THEIR PRODUCTION AND THEIR USE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2003-10-30 WO claimed
WO-2003080741-A1 DYE MIXTURES OF FIBRE REACTIVE AZODYES, PRODUCTION AND USE THEREOF DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2003-10-02 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050034252-A1 Dye mixtures of fiber-reactive azo dyes, their preparation and their use CRY1, FZD7, CBR3 ALDH1A1 617/4885TSHR 2434/4885HSD17B10 2946/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.