Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27627853 | 0.76 | CACNA2D1 (0.68) | KMT2AL3MBTL1MEN1HTTSIGMAR1 | |
| SCHEMBL1654788 | 0.76 | HTR1A (0.72) | KMT2AMEN1HTTSIGMAR1GAA | |
| SCHEMBL4494058 | 0.75 | SIGMAR1 (0.55) | KMT2AL3MBTL1MEN1KDM4ESIGMAR1 | |
| SCHEMBL25180786 | 0.73 | NPC1 (0.74) | PRCPKMT2AL3MBTL1LMNAALDH1A1 | |
| SCHEMBL5597718 | 0.73 | KMT2A (0.71) | KMT2ALMNASIGMAR1ALDH1A1GAA | |
| SCHEMBL4492195 | 0.72 | SIGMAR1 (0.54) | KMT2AMEN1LMNASIGMAR1METAP1 | |
| SCHEMBL3011662 | 0.72 | NPC1 (0.77) | PRCPKMT2AL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL9844038 | 0.72 | ALDH1A1 (0.60) | KMT2AL3MBTL1MEN1LMNAALDH1A1 | |
| SCHEMBL31167447 | 0.72 | KMT2A (0.94) | KMT2AL3MBTL1MEN1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL4820975 | 0.72 | ALDH1A1 (0.71) | KMT2ALMNASIGMAR1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433662-A2 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-26 | — | — | EP | claimed |