Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA4 | P22748 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2922201 | 0.85 | CA2 (0.39) | CA2CA4CA1CA6PTPN1 | |
| SCHEMBL25205732 | 0.82 | CA2 (0.37) | CA2CA4CA1CA6PTPN1 | |
| SCHEMBL6737749 | 0.82 | CA2 (0.37) | CA2CA4CA1CA6PTPN1 | |
| SCHEMBL20197841 | 0.79 | IMPDH2 (0.36) | HSD17B10 | |
| SCHEMBL12089524 | 0.77 | HSD17B10 (0.34) | HSD17B10 | |
| SCHEMBL21461783 | 0.77 | CA2 (0.37) | CA2CA4CA1CA6PTPN1 | |
| SCHEMBL107339 | 0.76 | HSD17B10 (0.36) | HSD17B10 | |
| SCHEMBL16071629 | 0.76 | HSD17B10 (0.32) | HSD17B10 | |
| SCHEMBL20253177 | 0.76 | MAPT (0.35) | CA2CA4CA1CA6 | |
| SCHEMBL3763099 | 0.76 | HSD17B10 (0.41) | CA2CA1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423991-A2 | Process for the preparation of 2-trifluoromethyl-4-hydroxybenzoic acid | Showa Shell Sekiyu Kabushiki Kaisha (JP) | 1991-04-24 | — | — | EP | disclosed |