SCHEMBL2922201

SCHEMBL2922201

COc1c(F)c(F)c(Br)c(F)c1F

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.39
CA4 P22748 3/20 0.39
CA1 P00915 1/20 0.39
CA6 P23280 1/20 0.39
PTPN1 P18031 1/20 0.37
HSD17B10 Q99714 1/20 0.35
ALOX5AP P20292 1/20 0.31
FEN1 P39748 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6737749 0.97 CA2 (0.37) CA2CA4CA1CA6PTPN1
SCHEMBL25205732 0.92 CA2 (0.37) CA2CA4CA1CA6PTPN1
SCHEMBL21461783 0.86 CA2 (0.37) CA2CA4CA1CA6PTPN1
SCHEMBL9844526 0.85 CA2 (0.33) CA2CA4CA1CA6PTPN1
SCHEMBL3763099 0.84 HSD17B10 (0.41) CA2CA1HSD17B10
SCHEMBL182607 0.81 HSD17B10 (0.40) CA2CA1HSD17B10
SCHEMBL21461786 0.78 CA2 (0.32) CA2CA4CA1CA6PTPN1
SCHEMBL31299646 0.78 MAPT (0.33) CA2CA4CA1CA6PTPN1
SCHEMBL23414125 0.78 CA2 (0.32) CA2CA4CA1CA6PTPN1
SCHEMBL14468297 0.78 PTPN1 (0.35) CA2CA4CA1CA6PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114671762-B Fluorine-containing bi-xylylene methacrylate cross-linking agent and preparation method thereof 长春市兆兴新材料技术有限责任公司 2024-03-19 CN claimed
CN-114671762-A Fluorine-containing biphenyl dimethacrylate crosslinking agent and preparation method thereof 长春市兆兴新材料技术有限责任公司 2022-06-28 CN claimed
CN-114671762-B Fluorine-containing bi-xylylene methacrylate cross-linking agent and preparation method thereof 长春市兆兴新材料技术有限责任公司 2024-03-19 CN disclosed
CN-114671762-A Fluorine-containing biphenyl dimethacrylate crosslinking agent and preparation method thereof 长春市兆兴新材料技术有限责任公司 2022-06-28 CN disclosed
US-8383862-B2 Salt compound, cationic polymerization initiator and cationically polymerizable composition ADEKA CORPORATION (JP) 2013-02-26 US disclosed
EP-2223948-B1 SALT COMPOUND, CATIONIC POLYMERIZATION INITIATOR AND CATIONICALLY POLYMERIZABLE COMPOSITION ADEKA CORP (JP) 2013-01-23 EP disclosed
US-20100267857-A1 SALT COMPOUND, CATIONIC POLYMERIZATION INITIATOR AND CATIONICALLY POLYMERIZABLE COMPOSITION ADEKA CORPORATION (JP) 2010-10-21 US disclosed
EP-2223948-A1 SALT COMPOUND, CATIONIC POLYMERIZATION INITIATOR AND CATIONICALLY POLYMERIZABLE COMPOSITION Adeka Corporation (JP) 2010-09-01 EP disclosed
US-6013198-A LIQUID CRYSTALLINE COMPOUNDS MODIFIED TO HAVE A TRIFLUOROMETHYLPHENYL GROUP OR TRIFLUOROMETHOXYPHENYL GROUP AS EXAMPLE OF KNOWN TERMINAL SUBSTITUENT; CHEMICAL STABILITY, HIGH VOLTAGE HOLDING RATIO, GOOD UV STABILITY CHISSO CORPORATION (JP) 2000-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100267857-A1 SALT COMPOUND, CATIONIC POLYMERIZATION INITIATOR AND CATIONICALLY POLYMERIZABLE COMPOSITION RFC5, RER1, ARF5 CA2 526/4885CA4 644/4885CA1 2134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.