Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | TOP2A | P11388 | 3/20 | 0.56 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.50 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13497296 | 0.89 | KDM4E (0.52) | KDM4EALDH1A1LMNATOP2ATOP2B | |
| SCHEMBL10625961 | 0.89 | KDM4E (0.53) | KDM4EALDH1A1LMNATOP2ATOP2B | |
| SCHEMBL10627016 | 0.89 | KDM4E (0.53) | KDM4EALDH1A1LMNATOP2ATOP2B | |
| SCHEMBL10874188 | 0.89 | KDM4E (0.52) | KDM4EALDH1A1LMNATOP2ATOP2B | |
| SCHEMBL2108243 | 0.89 | ALDH1A1 (0.64) | KDM4EALDH1A1LMNATOP2ATOP2B | |
| SCHEMBL4718738 | 0.89 | KDM4E (0.60) | KDM4EALDH1A1LMNATOP2ATOP2B | |
| SCHEMBL541544 | 0.88 | ALDH1A1 (0.62) | KDM4EALDH1A1LMNATOP2ATOP2B | |
| SCHEMBL541543 | 0.88 | ALDH1A1 (0.62) | KDM4EALDH1A1LMNATOP2ATOP2B | |
| Hydrochloric Acid SCHEMBL28459278 | 0.88 | ALDH1A1 (0.62) | KDM4EALDH1A1LMNATOP2ATOP2B | |
| Oxalic Acid SCHEMBL27745929 | 0.86 | ALDH1A1 (0.60) | KDM4EALDH1A1LMNATOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109912504-B | Quinoline carboxylic acid compound and preparation method and application thereof | 山东省联合农药工业有限公司 | 2020-11-10 | — | — | CN | disclosed |
| WO-2020199980-A1 | QUINOLINE CARBOXYLIC ACID COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 山东省联合农药工业有限公司 | 2020-10-08 | — | — | WO | disclosed |
| EP-0429304-A2 | Pyridone-carboxylic acid derivatives and their use as veterinary medicines | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-05-29 | — | — | EP | disclosed |
| US-4777175-A | (NAPHTHYRIDINE, QUINOLINE) CARBOXYLIC ACID | WARNER-LAMBERT COMPANY (US) | 1988-10-11 | — | — | US | disclosed |
| US-4771054-A | QUINOLINE CARBOXYLIC ACID | WARNER-LAMBERT COMPANY (US) | 1988-09-13 | — | — | US | disclosed |
| EP-0230274-A2 | Derivatives of 7-(azabicycloalkyl)-quinoloncarboxylic acid and -naphthyridoncarboxylic acid | BAYER AG (DE) | 1987-07-29 | — | — | EP | disclosed |
| US-4665079-A | QUINOLINE DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1987-05-12 | — | — | US | disclosed |
| EP-0117473-B1 | QUINOLONE CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND ANTIBACTERIAL COMPOSITIONS CONTAINING THEM | BAYER AG (DE) | 1987-01-28 | — | — | EP | disclosed |
| US-4638067-A | NAPHTHYRIDINE AND QUINOLINE CARBOXYLIC ACIDS | WARNER-LAMBERT CO. (US) | 1987-01-20 | — | — | US | disclosed |
| EP-0117474-B1 | QUINOLONE CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND ANTIBACTERIAL COMPOSITIONS CONTAINING THEM | BAYER AG (DE) | 1986-10-29 | — | — | EP | disclosed |
| EP-0168733-A2 | Process for the preparation of quinolinone and naphthyridoncarboxylic acids | BAYER AG (DE) | 1986-01-22 | — | — | EP | disclosed |
| US-4563459-A | FUNGICIDES AND BACTERICIDES FOR AGRICULTURAL USE | BAYER AKTIENGESELLSCHAFT (DE) | 1986-01-07 | — | — | US | disclosed |
| US-4563448-A | PHYTOPATHOGENS | BAYER AKTIENGESELLSCHAFT (DE) | 1986-01-07 | — | — | US | disclosed |
| US-4559341-A | Quinolonecarboxylic acids and antibacterial agents containing these compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1985-12-17 | — | — | US | disclosed |
| US-4559342-A | Quinolone acids and antibacterial agents containing these compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1985-12-17 | — | — | US | disclosed |
| EP-0121727-A1 | Bactericidal agent based on quinolonecarboxylic acids | BAYER AG (DE) | 1984-10-17 | — | — | EP | disclosed |
| EP-0118854-A1 | Bactericidal agent containing quinolone-carboxylic acids | BAYER AG (DE) | 1984-09-19 | — | — | EP | disclosed |
| EP-0117473-A1 | Quinolone carboxylic acids, process for their preparation and antibacterial compositions containing them | BAYER AG (DE) | 1984-09-05 | — | — | EP | disclosed |
| EP-0117474-A1 | Quinolone carboxylic acids, process for their preparation and antibacterial compositions containing them | BAYER AG (DE) | 1984-09-05 | — | — | EP | disclosed |
| EP-0113091-A1 | Microbiocidal agents based on quinolone-carboxylic acids | BAYER AG (DE) | 1984-07-11 | — | — | EP | disclosed |