Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844730 | 1.00 | ALDH1A1 (0.43) | ALDH1A1MAPTNPC1RAB9AHTR2A | |
| SCHEMBL9844734 | 1.00 | ALDH1A1 (0.43) | ALDH1A1MAPTNPC1RAB9AHTR2A | |
| SCHEMBL8946475 | 0.82 | CYP3A4 (0.46) | MEN1MAPK1KMT2A | |
| SCHEMBL8946490 | 0.82 | CYP3A4 (0.46) | MEN1MAPK1KMT2A | |
| SCHEMBL8946483 | 0.82 | CYP3A4 (0.46) | MEN1MAPK1KMT2A | |
| SCHEMBL8946545 | 0.71 | HTR2A (0.36) | ALDH1A1HTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL8946539 | 0.71 | HTR2A (0.36) | ALDH1A1HTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL8946537 | 0.71 | HTR2A (0.36) | ALDH1A1HTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL15888945 | 0.70 | HTR2C (0.42) | ALDH1A1MAPTNPC1RAB9AHTR2A | |
| SCHEMBL8946673 | 0.70 | HTR2A (0.40) | ALDH1A1MAPTHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409410-A1 | Indenoindole compounds | UNIVERSITY OF BATH (GB) | 1991-01-23 | — | — | EP | disclosed |