Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5674950 | 0.84 | KDM4E (0.50) | KDM4EBACE1TAAR1ALDH1A1HPGD | |
| SCHEMBL2129167 | 0.83 | TSHR (0.47) | KDM4EALDH1A1HPGDKMT2ATSHR | |
| SCHEMBL27822273 | 0.82 | KDM4E (0.50) | KDM4EBACE1TAAR1ALDH1A1HPGD | |
| SCHEMBL3877732 | 0.82 | KDM4E (0.50) | KDM4EBACE1TAAR1KMT2ACYP1A2 | |
| SCHEMBL27271137 | 0.81 | BACE1 (0.52) | KDM4EBACE1TAAR1ALDH1A1HPGD | |
| SCHEMBL13162416 | 0.81 | HPGD (0.55) | KDM4EBACE1ALDH1A1HPGDKMT2A | |
| SCHEMBL8764311 | 0.79 | BACE1 (0.42) | KDM4EBACE1TAAR1ALDH1A1HPGD | |
| SCHEMBL10621976 | 0.78 | BACE1 (0.43) | KDM4EBACE1TAAR1ALDH1A1HPGD | |
| SCHEMBL16190200 | 0.77 | CTSD (0.60) | KDM4EALDH1A1HPGDKMT2ACYP1A2 | |
| SCHEMBL6903284 | 0.77 | TSHR (0.58) | KDM4EALDH1A1HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406992-A2 | New non-ionic carboxamide contrast agent | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-01-09 | — | — | EP | claimed |