Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 3/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | TEK | Q02763 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 3/20 | 0.45 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 3/20 | 0.41 |
| ▸ | RET | P07949 | 2/20 | 0.40 |
| ▸ | EIF2AK3 | Q9NZJ5 | 3/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | ABL2 | P42684 | 1/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844770 | 0.87 | EP300 (0.49) | KDREP300SRCRETEGFR | |
| SCHEMBL27709073 | 0.83 | MBOAT4 (0.50) | EP300MBOAT4SLC16A3 | |
| SCHEMBL9844798 | 0.81 | PTGER1 (0.42) | KDRLCKTEKEP300SLC16A3 | |
| SCHEMBL9844757 | 0.80 | DHFR (0.55) | — | |
| SCHEMBL9844775 | 0.75 | DHFR (0.43) | — | |
| SCHEMBL9844769 | 0.75 | DHFR (0.43) | — | |
| SCHEMBL14647492 | 0.74 | ADORA2A (0.43) | EIF2AK3 | |
| SCHEMBL9844768 | 0.72 | TBXAS1 (0.39) | EP300MBOAT4 | |
| SCHEMBL18100426 | 0.67 | ADK (0.55) | KDRLCKSRCRETEIF2AK3 | |
| SCHEMBL22676116 | 0.66 | KDR (0.47) | KDRLCKTEKXDHSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438261-A2 | Condensed heterocyclic glutamic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-07-24 | — | — | EP | disclosed |