Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844795 | 0.83 | DHFR (0.60) | DHFRTYMS | |
| SCHEMBL9844996 | 0.82 | DHFR (0.62) | DHFRTYMS | |
| SCHEMBL9227836 | 0.80 | DHFR (0.57) | DHFRTYMS | |
| SCHEMBL9221909 | 0.79 | DHFR (0.59) | DHFRTYMS | |
| SCHEMBL9844834 | 0.77 | DHFR (0.69) | DHFRTYMS | |
| SCHEMBL9844841 | 0.77 | DHFR (0.56) | DHFRTYMS | |
| SCHEMBL9844756 | 0.77 | DHFR (0.56) | DHFRTYMS | |
| SCHEMBL9844911 | 0.77 | DHFR (0.56) | DHFRTYMS | |
| SCHEMBL9228475 | 0.76 | DHFR (0.53) | DHFRTYMS | |
| SCHEMBL9221596 | 0.76 | DHFR (0.55) | DHFRTYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438261-A2 | Condensed heterocyclic glutamic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-07-24 | — | — | EP | disclosed |