SCHEMBL9844906

SCHEMBL9844906

O=C1C=c2cc3ccc4ccccc4c3cc2=CC1.c1cc2cccc3c4cccc5cccc(c(c1)c23)c54

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.41
ERBB2 P04626 1/20 0.41
FYN P06241 1/20 0.41
MAOA P21397 1/20 0.41
ACHE P22303 1/20 0.41
AHR P35869 1/20 0.41
ALDH1A1 P00352 6/20 0.41
HSD17B10 Q99714 5/20 0.41
HIF1A Q16665 2/20 0.41
CYP1B1 Q16678 1/20 0.41
HPGD P15428 4/20 0.37
THRB P10828 1/20 0.37
TSHR P16473 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
MAPK1 P28482 1/20 0.35
CASP1 P29466 1/20 0.35
PAX8 Q06710 1/20 0.34
TDP1 Q9NUW8 3/20 0.33
CYP2A6 P11509 1/20 0.33
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23840 0.93 ALDH1A1 (0.47) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL5313840 0.93 ALDH1A1 (0.47) CYP1A2ERBB2FYNMAOAACHE
Benzanthrone SCHEMBL9018921 0.86 CASP1 (0.49) CYP1A2ERBB2FYNMAOAACHE
Ethylene Glycol SCHEMBL18525382 0.86 ALDH1A1 (0.41) CYP1A2ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL11515314 0.86 ALDH1A1 (0.41) CYP1A2ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL11154985 0.85 ALDH1A1 (0.38) CYP1A2MAOAAHRALDH1A1HSD17B10
SCHEMBL10704294 0.81 CES1 (0.35) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL31656985 0.81 ALDH1A1 (0.38) CYP1A2ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL31657027 0.81 ALDH1A1 (0.38) CYP1A2ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL31657085 0.81 ALDH1A1 (0.38) CYP1A2ALDH1A1HSD17B10HIF1ACYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0425142-A2 Positive acting photoresist and method of producing same ROHM AND HAAS COMPANY (US) 1991-05-02 EP disclosed