SCHEMBL9844964

SCHEMBL9844964

CCn1c(N2CCN(CCCCN)CC2)nc2ccccc21

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14431871 0.79 KMT2A (0.49) KMT2A
SCHEMBL9092075 0.78 HTR1A (0.62)
SCHEMBL16649554 0.77 KMT2A (0.68) KMT2A
SCHEMBL14432600 0.77 KMT2A (0.47) KMT2A
SCHEMBL14431906 0.76 NPSR1 (0.47) KMT2A
SCHEMBL10926483 0.76
SCHEMBL5512679 0.75 HTR3A (0.71) KMT2A
SCHEMBL14431867 0.74 ALDH1A1 (0.47) KMT2A
SCHEMBL15963205 0.74 KMT2A (0.64) KMT2A
SCHEMBL5241565 0.74 KMT2A (0.47) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0447345-A2 New Azaspyro [4.5] decane-7,9-dione derivatives FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (FAES) (ES) 1991-09-18 EP disclosed